Population biology of the human restricted pathogen, Streptococcus pyogenes
نویسندگان
چکیده
منابع مشابه
Essential Genes in the Core Genome of the Human Pathogen Streptococcus pyogenes
Streptococcus pyogenes (Group A Streptococcus, GAS) remains a major public health burden worldwide, infecting over 750 million people leading to over 500,000 deaths annually. GAS pathogenesis is complex, involving genetically distinct GAS strains and multiple infection sites. To overcome fastidious genetic manipulations and accelerate pathogenesis investigations in GAS, we developed a mariner-b...
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Streptococcus pyogenes (S.pyogenes) is the cause of many important human diseases, ranging from mild superficial skin infections to life-threatening systemic diseases. This pathogen of interest for the therapeutic drug target is the one causing contamination in food samples. The samples (contaminated vegetables) subjected to serial dilution was used as inoculums for the Nutrient agar (NA) plate...
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Selected reaction monitoring mass spectrometry (SRM-MS) is a targeted proteomics technology used to identify and quantify proteins with high sensitivity, specificity and high reproducibility. Execution of SRM-MS relies on protein-specific SRM assays, a set of experimental parameters that requires considerable effort to develop. Here we present a proteome-wide SRM assay repository for the gram-p...
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UNLABELLED For over a century, a fundamental objective in infection biology research has been to understand the molecular processes contributing to the origin and perpetuation of epidemics. Divergent hypotheses have emerged concerning the extent to which environmental events or pathogen evolution dominates in these processes. Remarkably few studies bear on this important issue. Based on populat...
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Objective(s): Streptokinase (SKa) is an antigenic protein which is secreted by Streptococcus pyogenes. Streptokinase induces inflammation by complement activation, which may play a role in post infectious diseases. In the present study, recombinant streptokinase from S. pyogenes was produced and showed that recombinant SKa protein was recognized by infected human sera using Western blot analy...
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ژورنال
عنوان ژورنال: Infection, Genetics and Evolution
سال: 2009
ISSN: 1567-1348
DOI: 10.1016/j.meegid.2009.03.002